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Healthy life
We saw an increased risk of developing pancreatic cancer by 22% in those who drank two or more types of alcoholic drinks a day compared with those who do not drink alcohol, "said study author Jeanine M. Genkinger, PhD, an assistant professor of oncology of the Lombardi Comprehensive Cancer Center at Georgetown University, Washington, DC
Pancreatic cancer is often deadly because it is difficult to be detected early. This cancer is found at about 38,000 people in the United States in 2008. Approximately 6% of cancer deaths in America in 2008 was associated with pancreatic cancer both in men and women.
Alcohol and pancreatic cancer: Study details
Research on alcohol intake as risk factors for pancreatic cancer has found mixed results. Large amounts of alcohol consumption is associated with chronic inflammation of the pancreas and diabetes type 2, both of these is associated with an increased risk of pancreatic cancer. However, studies on alcohol is not clear.
Therefore, Genkinger and his friends gathered results from 14 previous studies that have been published regarding alcohol intake and pancreatic cancer involving nearly 863,000 men and women, with available data on their dietary habits before the cancer was diagnosed.
In the study sample, 2187 men and women diagnosed with pancreatic cancer. First, the team Genkinger see men and women, and found the risk increased by 22% with 2 or more alcoholic beverages a day. One drink is defined through the standard, 12-ounce beer, 4 ounces of wine, or 1.5 ounces of liquor.
"When we see men and women separately, women who drank 2 or more a day increased risk by 41% compared with those who do not drink," said Genkinger. "This statistic is very significant."
Men who drank 2 or more alcoholic drinks a day increased risk by 12% compared with those who do not drink, which was not statistically significant.
Then they looked further. When men drink more than 3, the risk was increased nearly reached 60% compared with those who are not drinkers, with particular regard to certain types of pancreatic cancer, adenocarcinoma. This be an significant relationship. Most pancreatic cancers are adenocarcinomas.
The same effect seen regardless of type of alcohol is drunk, he explained. "This is not related to the type of beverage, but related to total alcohol intake."
The reason why alcohol increases the risk of cancer is as yet unknown, but one of several theories stating that the by-products of alcohol metabolism is a carcinogen. The researchers also found that obesity is closely related to pancreatic cancer and smoking is also one risk factor for pancreatic cancer.
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